Stanley Chen
3 days ago

Actively Maintained Therapeutics Pipeline - Lifespan.io

Actively Maintained Therapeutics Pipeline - Lifespan.io

Hey all, came across a really nice overview of the different therapeutic targets and methods used in the Longevity space Feel free to connect on LinkedIn, I'm an Investor that posts about Bioscience Investments, Computational Biology, and Advanced Bioinformatics: https://www.linkedin.com/in/stanleyyhc/
Julian West
4 months ago

2022 LONGEVITY FUNDING Deals by Type

2022 LONGEVITY FUNDING Deals by Type

Did you know: Altos Labs raised $3 billion in series A in 1/2022! 2022 LONGEVITY FUNDING Deals by Type. Notice the preeminence of Series A and Seed. For more fascinating info: https://spannr.com/reports/2022-longevity-funding Want to get more involved? Check out the Alliance for Longevity Initiatives (A4LI), a non-pro...
Jessie MacAlpine
6 months ago

Reindeer Provide Insight into Mammalian Wound Healing

Julian West
7 months ago

NLRP3 - Aging and Chronic Inflammation (beyond Senescent Cells)

NLRP3 - Aging and Chronic Inflammation (beyond Senescent Cells)

Every poignant dramatic story has an arch-villain. The aging process has many! A well-known one is chronic inflammation - sometimes referred to as "Inflammaging" (the vicious cycle between inflammation and aging.) An often-discussed source of chronic inflammation are senescent cells - but they aren't the only one. The N...
LongevityCell BiologyPharmacologyInflammasomes IL-1β IL-18 Life123 CANTOS BioAge Labs Inflammation Inflammaging NLRP3 Pyroptosis Healthspan
Julian West
8 months ago

Desperately short telomeres? Alternate way to elongate them!

Desperately short telomeres? Alternate way to elongate them!

Once in a while, a paper gives a feeling of "Wow, at a junction in History!" Such is a recent entry in Nature Cell Biology, which I will liken to a play: Prelude - Telomere (DNA protective caps) shortening : one of the first recognized "hallmarks of aging"... (general background from NIH: https://www.ncbi.nlm.nih.gov/pmc/...
Julian West
9 months ago

Removing Toxic Biomolecules that Accumulate with Age

Removing Toxic Biomolecules that Accumulate with Age

Something I love about scientific conferences is being exposed to less widely known - but potentially very important - avenues of research. Case in point: the accumulation of a toxic biomolecule, an oxidized form of cholesterol (7-ketocholesterol : https://pubchem.ncbi.nlm.nih.gov/compound/7-Ketocholesterol ), believed to ...
LongevityCell BiologyPharmacologyCholesterol Atherosclerosis Cyclodextrins 7-ketocholesterol Cyclarity Therapeutics Matthew O'Connor Conferences Ending Age-Related Diseases 2022 UDP-003 Candymer software Healthspan
Julian West
9 months ago

Restoring the function of the aging Thymus - clinical trials

Restoring the function of the aging Thymus - clinical trials

One extraordinary presentation at "Ending Age-Related Diseases 2022 " was by Greg Fahy, on past and new clinical trials to regenerate the thymus - a gland which sadly shrinks in age, and is a key player in the immune system. The initial human clinical trial was named "TRIIM", at Stanford (2015-17), with notable results. ...
LongevityConferences Greg Fahy Metformin DHEA Growth Hormones Intervene Immune TRIIM Clinical TrialsEpigeneticsThymus Healthspan Healthy Aging
Julian West
9 months ago

Details emerge about MECHANISM of the "INDEFINITE" LIFESPAN of a type of jellyfish

Julian West
9 months ago

Imminent Online/Onsite Conference: the 9th annual "Aging Research & Drug Discovery"

Julian West
9 months ago

Horvath Epigenetic clocks : from the "Ending Age-Related Diseases 2022" conference